Abstract: The development and evolution of the Ordovician and Jurassic sedimentary systems are explored on the basis of sedimentary facies distribution and regional tectonism of the Palaeozoic and Mesozoic strata on the southern slope of the Huimin depression, Shandong. The results of research indicate that the study area was covered by a succession of carbonate tidal-flat sedimentary systems during the Early Palaeozoic; terrestrial-marine deltaic sedimentary systems during the Late Palaeozoic, and continental fluvial sedimentary systems during the Mesozoic. The deltaic sedimentary systems consist dominantly of Carboniferous marine deltaic and Permian continental lacustrine deltaic sedimentary systems. The region studied has recorded the multiphase evolution of Palaeozoic and Mesozoic tectonism and sedimentation. In places, some strata are absent due to tectonic uplift. Spatially the differences in subsidence and deposition are noticeable in the Late Palaeozoic and Mesozoic strata.