Abstract: Three kinds of deep seismic probing,near-vertical reflections ,refraction and wide-angle reflec-tions and broadband seismic observations ,have been carried out along the corridor of the Xinjiang geo-science transect.They have revealed the lithospheric structure and lateral variations across the West Kunlun orogen-Tarim block-Tianshan orogen.Seismic evidence of collision between the Tarim block and West Kunlun orogen on the northwestern Qinghai-Tibet plateau has been found and the basin-and-range cou-pling relationships between the Tarim basin and Tianshan,the Tianshan and Junggar basin,the West Kun-lun and Tarim basin at the lithospheric scale have been revealed too.Comparative study shows that the deep process of the collision and deformation on the northern margin of the Qinghai-Tibetan plateau is different from that on its southern margin.