Abstract: In order to probe into the features of uplift in the Great Canyon Region of the Yalung Zangbo River, the authors extracted the morphologies of the Yalung Zangbo River and the Parlung Zangbo River from DEM and remote sensing images, and analyzed them by adopting Hack profile, SL index and the model of Amos river width. The Hack profile of the Yalung Zangbo River which is below Datogka area assumes a convex shape. In this area, the SL index increases and the width of the river decreases. In the Tibet Bubba East Falls, the top of the Great Canyon, the SL index reaches the maximum while the width of the river reaches the minimum. In the river which is below the top of the Great Canyon, the SL index decreases whereas its width becomes wider. In the Parlung Zangbo River which is below Guxiang Village, the SL index increases whereas the width of the river decreases. Combined with the morphology of the two rivers and the regional geological and geographical background, the authors hold that the uplift of the Brahmaputra Great Bend area was heterogeneous, which entered the section with dramatically increasing uplift near Datogka area. The segment which had the strongest uplift is in the possession of Bubba East Falls, the top of the Great Canyon, and after that the Yalung Zangbo River was gradually away from the central area of the uplift.