Abstract: The Dawujian deposit is a typical stratabound skarn W-Mo deposit located on the northeastern margin of the Qin-Hang metallogenic belt. The determination of the ages of the mineralization and the magmatic rocks of the Dawujian deposit is very important for the study of deposit genesis and regional metallogenic regularity. On the basis of geological and petrographic studies, the authors collected the primary types of magmatic rocks and molybdenite of the main mineralization stage and obtained the ages of the magmatic rocks (148.3±2.2Ma, 148.5±2.1Ma) by LA-ICP-MS zircon U-Pb dating and the age of mineralization（144.4±1.5Ma）by Re-Os dating of the Dawujian deposit. The authors also reveal that the Dawujian deposit was formed by magmatite intrusion of the first stage of Yanshanian period（150~136Ma）. This stage seems to be an important metallogenic period in the south of Anhui Province, which was formed in a regional compressional environment from the transform of the Paleo-Tethys tectonic domain to the Pacific tectonic domain.